Qingshan Wei
Department of Chemical and Biomolecular Engineering
Associate Professor
College of Engineering
3318 Plant Sciences Building
919-515-3154 qwei3@ncsu.eduBio
My research is focused on developing next-generation field-deployable molecular imaging, sensing, and diagnostic tools for plants and human. These tools are essential to translate conventional laboratory diagnostic tests from the bench to the point of care for rapid field detection, personal health monitoring, as well as battling infectious diseases in the resource-limited settings. My group is currently studying two main research schemes, including the development of new portable microscopy devices for single-molecule detection as well as novel lab-on- a-chip systems for rapid sample preparation such as DNA extraction, amplification, and sequence-specific labeling. We also develop nanophotonics enhanced molecular diagnostic assays towards ultra-sensitive analysis. Our work spans broadly at the interface of engineering, chemistry, nanoscience, and biology.
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Publications
Honors and Awards
- Honorable Mention, the Chancellor’s Award for Postdoctoral Research, UCLA
- Bilsland Dissertation Fellowship, Purdue University
Education
Postdoc Bioengineering University of California - Los Angeles 2016
Ph.D. Chemistry Purdue University 2012
M.S. Polymer Materials and Engineering Zhejiang University 2007
B.S. Polymer Materials and Engineering Zhejiang University 2005
Publications
- A compartment-free digital plasmonic coupling assay via single-particle imaging and counting , NANOSCALE ADVANCES (2025)
- A digital nonenzymatic nucleic acid amplification assay for ultrasensitive detection of cell-free microRNA in human serum , SENSORS & DIAGNOSTICS (2025)
- A dual-functional needle-based VOC sensing platform for rapid vegetable phenotypic classification , BIOSENSORS & BIOELECTRONICS (2025)
- CRISPR-Cas based platforms for RNA detection: fundamentals and applications , CHEMICAL COMMUNICATIONS (2025)
- Editorial: The use of volatile organic compounds in sustainable management of pests and diseases , FRONTIERS IN HORTICULTURE (2025)
- From Lab to Market: Paper-Based CRISPR Diagnostics and Commercialization Pathways , ADVANCED SENSOR RESEARCH (2025)
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Non‐destructive seed genotyping via microneedle‐based
DNA extraction , Plant Biotechnology Journal (2025) - Purification of CRISPR Cas12a from E. coli cell lysates using peptide affinity ligands , JOURNAL OF CHROMATOGRAPHY A (2025)
- Shape and size-dependent surface plasmonic resonances of liquid metal alloy (EGaIn) nanoparticles , NANOSCALE (2025)
- Smartphone-Based Colorimetric VOC Sensor for Early Detection of Phytophthora Ramorum in Rhododendrons , ACS Sensors (2025)