Marce Lorenzen
Bio
The Lorenzen laboratory is part of the Genetic Pest Management (GPM) program at North Carolina State University. Currently our main research project is to elucidate the molecular mechanism that underlies a novel class of selfish-genetic elements found only in Tribolium flour beetles. Due to the selfish behavior of these―Medea‖ elements, they may be useful as gene “drivers” to push pesticide susceptibility into populations of insect pests of crops, or vector incompetence into populations of insect vectors of disease. For example: to force an anti-malarial gene into a mosquito population.
Education
B.S. University of Rhode Island
Ph.D. Kansas State University
Area(s) of Expertise
To elucidate the molecular mechanism that underlies a class of novel selfish-genetic element found only in Tribolium. Due to the selfish behavior of these elements they have potential as gene "drivers" to push pesticide susceptibility into populations of insect pests of crops, or vector incompetence into populations of insect vectors of disease.
Publications
- CRISPR/Cas9‐mediated genome editing of Frankliniella occidentalis, the western flower thrips, via embryonic microinjection , Insect Molecular Biology (2024)
- Development of an agroinfiltration-based transient hairpin RNA expression system in pak choi leaves (Brassica rapa ssp. chinensis) for RNA interference against Liriomyza sativae , PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY (2024)
- Evaluation of Peregrinus maidis transformer-2 as a target for CRISPR-based control , PLOS ONE (2024)
- The Genome of Arsenophonus sp. and Its Potential Contribution in the Corn Planthopper, Peregrinus maidis , INSECTS (2024)
- A draft Diabrotica virgifera virgifera genome: insights into control and host plant adaption by a major maize pest insect , BMC Genomics (2023)
- An Optimized Small-Scale Rearing System to Support Embryonic Microinjection Protocols for Western Corn Rootworm, Diabrotica virgifera virgifera , Insects (2023)
-
Development of transgenic corn planthopper
Peregrinus maidis , Insect Molecular Biology (2023) - Genome and Genetic Engineering of the House Cricket (Acheta domesticus): A Resource for Sustainable Agriculture , Biomolecules (2023)
- Structural and functional insights into the ATP-binding cassette transporter family in the corn planthopper, Peregrinus maidis , Insect Molecular Biology (2023)
- The Genome of Rhyzopertha dominica (Fab.) (Coleoptera: Bostrichidae): Adaptation for Success , Genes (2022)