David Rasmussen

Bio

David Rasmussen joined the DEPP faculty in 2018 as part of the Emerging Plant Disease and Global Food Security Cluster.

Area(s) of Expertise

David leads the Phylodynamics Research Group at NC State which develops new phylogenetic and computational methods for genomic epidemiology. Recent work by the group has centered around quantifying the fitness of viral pathogens in terms of their transmission potential between hosts using genomic sequence data. David's group also studies how plant viruses such as Tomato spotted wilt virus adapt to novel hosts and expand their host range by resolving fitness tradeoffs between hosts.

Publications

• Exploring the Accuracy and Limits of Algorithms for Localizing Recombination Breakpoints , MOLECULAR BIOLOGY AND EVOLUTION (2024)
• Quantifying the strength of viral fitness trade-offs between hosts: a meta-analysis of pleiotropic fitness effects , EVOLUTION LETTERS (2024)
• Diversity and Pathobiology of an Ilarvirus Unexpectedly Detected in Diverse Plants and Global Sequencing Data , PHYTOPATHOLOGY (2023)
• Espalier: Efficient Tree Reconciliation and Ancestral Recombination Graphs Reconstruction Using Maximum Agreement Forests , SYSTEMATIC BIOLOGY (2023)
• Evolutionarily diverse origins of deformed wing viruses in western honey bees , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2023)
• Epidemiology of Plasmid Lineages Mediating the Spread of Extended-Spectrum Beta-Lactamases among Clinical Escherichia coli , MSYSTEMS (2022)
• Plasmodium falciparum Genetic Diversity in Coincident Human and Mosquito Hosts , MBIO (2022)
• Recombination-aware phylogeographic inference using the structured coalescent with ancestral recombination , PLOS COMPUTATIONAL BIOLOGY (2022)
• The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance , SCIENCE (2022)
• A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa , SCIENCE (2021)