Giuseppe Valacchi

Bio

Giuseppe Valacchi is a David H. Murdock Distinguished Professor and Professor of Regenerative Medicine at North Carolina State University. In addition, he is an International Scholar at Kyung Hee University, Seoul, South Korea. He obtained his BS (Physiology) with Laude, his M.S. in Physiopathology and his Ph.D. in Cellular Physiology and Neuroimmuno-Physiology from the University of Siena, Italy. 

His research has been focused in understanding the cellular and molecular redox mechanisms that define the tissues physio-pathological responses to endogenous and exogenous factors (Exposome)  with special focus on target tissues such as skin and respiratory tract.

He is the author of over 300 peer reviewed international manuscripts, 20 book chapters, and 4 books. He has been a member of the Society of Free Radical Research -Europe (SFRR-Europe) Council from 2017 to 2021. From 2023 he is the SFRR-Europe President Elect. He has won several awards, among them the Entelligence Award from Actelion, the Exposome Award, the University of Ferrara Bronze Medal (2020 from the Rector of Ferrara, Prof. Zauli). In 2018 he was awarded with the “Doctorate Honoris Causa” in Biochemistry and Pharmacy from the University of Buenos Aires.  In 2019 he was the recipient of the Clinical Research award from the SFRR-E and in 2021, he was awarded in Rome, as “Paladin of Health” from the Italian Ministry of Public Health and Education. In 2022, he was nominated and awarded with the title of “Faculty Scholar” at North Carolina State University, a title that recognizes and rewards emerging academic leaders who demonstrate significant achievement. From 2022 he is a David H. Murdock Distinguished Professor in Regenerative Medicine at NCSU.

He is Editor for Archives in Biochemistry and Biophysics and for Redox Experimental Medicine; Associate Editor for Oxidative Medicine and Cellular Longevity, Mediators of Inflammation, Biomed (dermatology); member of the Editorial board of several international journals including, Free Radicals in Biology and Medicine, Antioxidants, Biofactors, Genes and Nutrition.

H index: 69 (scholar), 56 (Scopus)

Area(s) of Expertise

Redox Biology
Focus Area: Rare diseases such as Autism and Rett Syndrome; exposome effect on target tissues, skin, lung and GI tract

Publications

• Design and Characterization of a Transethosome‐Based Gel for Cutaneous Administration of Genistein , Journal of Nanotechnology (2026)
• Exogenous myrosinase from mustard seed increases bioavailability of sulforaphane from a glucoraphanin-rich broccoli seed extract in a randomized clinical study , Scientific Reports (2026)
• Oxysterol-induced oxidative disruption of skin junction integrity , Free Radical Biology and Medicine (2026)
• Therapeutic Potential of Ozonized Glycerin in Skin Inflammation and Repair , Cosmetics (2026)
• 64779 The impact of UV and diesel damage in cutaneous tissue and the protective role of a topical antioxidant containing vitamin C, E and ferulic acid on biomarkers related to skin aging , Journal of the American Academy of Dermatology (2025)
• Abnormal MAMs proteins can disrupt finely tuned signaling between ER and mitochondria in RTT brain , Free Radical Biology and Medicine (2025)
• Application of Antioxidant Mixture Prevents Cutaneous “Oxinflammaging” in Subjects Exposed to Particulate Matter , Journal of Cosmetic Dermatology (2025)
• Berry Fruit Extracts as Topical Cosmeceuticals for Skin Health Applications: A Systematic Review , Cosmetics (2025)
• Cadmium exposure affects the progression of human metastatic melanoma by inducing a deregulation of antioxidant cell response , Free Radical Biology and Medicine (2025)
• Comparing UV and Diesel Cutaneous Damage and Evaluating the Protective Role of a Topical Antioxidant Mixture Containing Vitamin C, E and Ferulic Acid , Experimental Dermatology (2025)

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