Bill Thompson
Distinquished University Professor
Plant and Microbial Biology, Genetics, and Crop Science
Faculty
Partners Building II 1205
Area(s) of Expertise
My two main research projects at present involve DNA replication and epigenetics. One is a large collaboration involving colleagues at three major institutions that seeks to characterize DNA replication programs in Arabidopsis and maize under different developmental circumstances and elucidate the mechanism whereby epigenetic marks are transmitted to daughter chromosomes in mitosis. The other is a local collaboration with Dr. George Allen in which we seek to clarify the molecular mechanism by which matrix attachment regions affect transgene expression and silencing.
Publications
- Chromatin structure profile data from DNS-seq: Differential nuclease sensitivity mapping of four reference tissues of B73 maize (Zea mays L), DATA IN BRIEF (2018)
- Genome-Wide Analysis of the Arabidopsis Replication Timing Program., Plant physiology (2018)
- Genomic Analysis of the DNA Replication Timing Program during Mitotic S Phase in Maize (Zea mays) Root Tips., The Plant cell (2017)
- Repliscan: a tool for classifying replication timing regions., BMC bioinformatics (2017)
- A flow cytometric method for estimating S-phase duration in plants., Journal of experimental botany (2016)
- Isolation of plant nuclei at defined cell cycle stages using EdU labeling and flow cytometry, Plant Cell Division: Methods and Protocols (2016)
- Defining multiple, distinct, and shared spatiotemporal patterns of DNA replication and endoreduplication from 3D image analysis of developing maize (Zea mays L.) root tip nuclei, Plant Mol. Biol. (2015)
- In vivo mapping of Arabidopsis scaffold/matrix attachment regions reveals link to nucleosome-disfavoring poly(dA:dT) tracts, Plant Cell (2014)
- A maize root tip system to study DNA replication programmes in somatic and endocycling nuclei during plant development, J. Exp. Bot. (2014)
- Starch self-processing in transgenic sweet potato roots expressing a hyperthermophilic α-amylase., Biotechnology progress (2011)
Education
Ph.D., Plant Physiology, University of Washington (1970)
B.A., Biology, Princeton University (1966)