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Tom Makris


Polk Hall 351


Research Interests

  • Natural product biosynthesis
  • Non-ribosomal peptides
  • Bioinorganic and biophysical chemistry
  • Oxygen activation
  • Sustainable chemistry
  • Biofuels



B.A. Biology University of Pennsylvania 1996

Ph.D. Biophysics University of Illinois Urbana-Champaign 2004

Post Doctoral Fellow University of Minnesota 2012

Area(s) of Expertise

My laboratory is interested in the chemical biology of enzymes involved in pharmaceutical biosynthesis and bioenergy production. We are interested in developing tools to understand the detailed molecular mechanisms of these potent catalysts, and ultimately leverage them for the synthesis of natural products of pharmacological or industrial importance. As a result, we utilize a large spectrum of techniques in our studies, ranging from genome mining, molecular biology, metabolic engineering, enzymology, transient kinetics, and biophysical spectroscopy.