Tom Makris

Bio

Research Interests

• Natural product biosynthesis
• Non-ribosomal peptides
• Bioinorganic and biophysical chemistry
• Oxygen activation
• Sustainable chemistry
• Biofuels

Area(s) of Expertise

My laboratory is interested in the chemical biology of enzymes involved in pharmaceutical biosynthesis and bioenergy production. We are interested in developing tools to understand the detailed molecular mechanisms of these potent catalysts, and ultimately leverage them for the synthesis of natural products of pharmacological or industrial importance. As a result, we utilize a large spectrum of techniques in our studies, ranging from genome mining, molecular biology, metabolic engineering, enzymology, transient kinetics, and biophysical spectroscopy.