Sample Preparation and Molecular Analysis - Polk 134
BioTek Cytation 5
BioTek Cytation 5 combines automated digital microscopy and conventional microplate detection in a configurable, upgradable platform. The microscopy module offers up to 40x magnification in fluorescence, brightfield, and color brightfield for maximum applications reach. The multi-mode detection modules include filter- and monochromator-based fluorescence detection, luminescence and UV-Vis absorbance detection.
Labconco Freeze Dryer
Low temperature of -85° C; for low eutectic point samples containing water or acetonitrile. Not for use with samples containing methanol or ethanol. Collector is capable of removing 2.2 liters of water in 24 hours.*. Collector coil and chamber are made of stainless steel.
The Geno/Grinder is an automated high-throughput plant and animal tissue homogenizer. It can accommodates a full range of sample vials from 2mL to 50mL centrifuge tubes or up to six deep-well titer plates. It is specifically designed for rapid cell disruption, cell lysis and tissue homogenization through bead beating. This enables fast and efficient extraction of nucleic acids, proteins and other molecules.
Beckman XL90 Ultracentrifuge
The Beckman Optima XL-90 Ultracentrifuge is a high performance solution designed to perform 100,000 rpm with centrifugal forces that reach up to 802,400 g. Its ESP Efficient Sedimentation Program stimulates gradient formation and sample separations.
Li-Cor Odyssey CLx
The Odyssey CLx is a next generation multifunctional imaging platform that can be used for a wide range of applications including quantitative Western blots, in cell Western blots, tissue section imaging, Coomassie protein gel imaging, nucleic acid gel imaging, glycoprotein detection, and gel shift assays. Its broad dynamic range greatly enhances sensitivity and reproducibility over older methods of detection.
Beckman JXN-30 Centrifuge
Biomolecular Interactions - Polk 41
Beckman Proteome Lab XL-A
Proteome Lab XL-A: Analytical Ultracentrifugation (AUC) is a non-destructive technique used to assess the size and shape of macromolecules. It can also be used to assess multimerization states and binding constants for intermolecular interactions.
Applied Photophysics CD
Structural, kinetic and thermodynamic information about macromolecules can be derived from circular dichroism spectroscopy. CD can be used to observe how secondary structure changes with environmental conditions or upon interaction with other molecules.
Surface plasmon resonance allows real-time, label-free detection of biomolecular interactions. Target molecules, usually proteins, are immobilized on a prepared gold sensor surface and a sample containing a potential interacting partner in solution is injected over the surface through a series of flow cells.