Michael Goshe

Bio

Proteomics: quantifying changes in protein abundance and probing post-translation modifications

Structural mass spectrometry:  developing novel cross-linking reagents to probe protein-protein and protein-ligand interactions and developing methods to probe protein-protein interactions at amino acid residue resolution using covalent H/D exchange

Publications

• CEPR1 regulates Arabidopsis thaliana root architecture by modulating auxin production via NIT1 , The Plant Journal (2025)
• Abstract 1847: Identifying the enzyme responsible for initiating aerobic acetylene metabolism in Rhodococcus rhodochrous ATCC 33258 , Journal of Biological Chemistry (2023)
• Tizoxanide Antiviral Activity on Dengue Virus Replication , Viruses (2023)
• Identification of multiple proteins whose interaction with mannitol dehydrogenase is induced by salicylic acid: Implications for unconventional secretion , PROTEOMICS (2021)
• Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis , Nature Communications (2020)
• Quantitative proteomic analysis of the tizoxanide effect in vero cells , Scientific Reports (2020)
• Proteomic method to extract, concentrate, digest and enrich peptides from fossils with coloured (humic) substances for mass spectrometry analyses , Royal Society Open Science (2019)
• Public questions spur the discovery of new bacterial species associated with lignin bioconversion of industrial waste , Royal Society Open Science (2019)
• Targeted Capture of Chinese Hamster Ovary Host Cell Proteins: Peptide Ligand Discovery , International Journal of Molecular Sciences (2019)
• Sucrose Nonfermenting 1-Related Protein Kinase 1 Phosphorylates a Geminivirus Rep Protein to Impair Viral Replication and Infection , PLANT PHYSIOLOGY (2018)