of Plant Biology
Permanent Resident (Green Card)
4213 Gardner Hall
Raleigh, NC 27695-7612
Phone (919) 513 0076
Fax (919) 515 3436
1993 Doctor of Sciences, Institute of Plant Biochemistry, Univ.of
Prof. H.W. Heldt, Prof. D. Robinson, advisors
“Accumulation and translocation of assimilates: subcellular volumes
and metaBOlite concentrations in leaves of barley and spinach”
1990 Diploma (MS), Institute of Plant Biochemistry, University
of Göttingen, Germany
1986 Bachelor of Sciences in Biology, University of Göttingen, Germany
Assistant Professor, 04/2005 – present, Dept. Plant Biology,
NC State University, USA
Research Assistant Professor, 12/2003 – 04/05, Dept. Plant Biology, NC State University, USA
Research Director, Sept. 2002 – 2003: Plant Gravitational Genomics, Dept of Plant Biology, NC State University, USA
Assistant Professor, Dec. 1998 – Sept. 2002, Dept. Biology, Univ. of Osnabrück, Germany
Research Associate, June 1996-Nov. 1998, NASA Specialized Center for Research and Training (NSCORT), Department of Plant Biology, NC State University, USA, Supervisor: Prof. Steven C. Huber,
Humboldt-Fellow, 1995-1996, Department of Plant Biology, University of Western Australia, Australia, Host: Prof. Craig Atkins
Humboldt-Fellow, 1994-1995, School of Biological Sciences, Flinders University of South Australia, Adelaide, Host: Dr. Kathryn Schuller
Research Associate, 1993, Institute of Plant Physiology, Göttingen, Germany
Research Assistant 1988-1993 Institute of Plant Biochemistry, Göttingen, Germany,
“Advanced Plant Physiology” (BO751) Spring 2006, 3 credts, NCSU.
“Computational Biology” (BO595D, BIT 595D), Fall 2005, 1 credit, NC State University
"Plant Biochemistry" Fall/Winter 1999-2001, graduate
course (2h/week, 16 weeks)
University Osnabrück, Germany.
"Introduction to Bioinformatics", Spring/Summer 2000/2001,
(2h/week, 14 weeks) University Osnabrück, Germany
The aim of this course was to introduce Biology graduate students to the basic algorithms underlying computational analysis of biological sequences.
"Plant Physiology" Spring 1999-2002, undergraduate course, (24h block) University Osnabrück
“Plant Gravitational Genomics and Space Biology” BO101, Perspectives on Plant Biology, Fall 2004.
“NASA’s Space Exploration – human or roBOtic – money well spent?” STS 302, Contemporary Science, Technology and Human Values. Fall 2004.
“Advanced Plant Physiology", Fall 1998,1997, and 2003, BO 551 Department, Plant Biology, NC State University
”Microarrays for Space“ Guest lecture on microarray analysis in BIT 815J (2003/04)
"Special Topics in Plant Physiology" Spring/Summer 1999, graduate course,
(2h/week, 14 weeks), University Osnabrück, Germany.
"Plant Physiology Seminar" Fall/ Winter 1999-2001, graduate course, (2h/week, 16 weeks), University Osnabrück, Germany.
"Modern Methods in Plant Biology" Spring 2002, graduate
course, (2h/week, 14 weeks), University Osnabrück, Germany.
"Bioinformatics" graduate course, Spring 2000 and 2001, University Osnabrück
(3h/week, 14 weeks). This class allowed students to analyze information based on the lecture course “Introduction to Bioinformatics”.
"Plant Physiology I" undergraduate course, Spring 200 and 2001, (2 week block, 5h/day) University Osnabrück
"Plant Physiology II - Molecular Biology", undergraduate
course, Winter 2000/2001/2002,
(2 week block, 8h/ day), University Osnabrück
"Plant Physiology III - Cell Biology", graduate course,
(6 week block, Lab internships),
Instructor, “Gravity & Plants: A Workshop for High School Teachers”,
July 1998, 1997,1996, Department of Plant Biology, NC State University
Teaching Assistant 1989-1994 Introduction to Biochemistry, Advanced Biochemistry I
Advanced Biochemistry II, University of Göttingen, Germany
GRADUATE STUDENTS AND POSTDOCTORAL ASSOCIATES:
Julia Frank (2002) Protein:protein interactions of cellulose synthase CesA1
Tanja Danker (2002) Identification of hexokinase genes from monocotyledons.
Daniela Holtgraewe (2001-2004): The physiological function of protein interactions between sucrose synthase, the cytoskeleton and cellulose synthesis.
Anke Thilo (2001-2004): Interactions of glycolytic enzymes in plants
Jeffrey Kimbrough (2003 – current): The transcriptional network of gravity signal transduction in Arabidopsis root tips
Anna Brogan Mann (2005-current) Response and Adaptation of an exotic library introgression lines from wild and domesticated tomato to extreme environments.
Dr. Raul Salinas-Mondragon (2003-current): Effects of altered phosphoinositol metabolism on transcript profiles during gravitropism.
Dr. Henrietta Myburg (2004-current): Transcriptional and translational regulation of gravitropism in maize pulvini
Dr. Mariya Khodakovskaya (2005-present): Effects of genetically altered Ca2+ pools and fluxes on stress tolerance and disease resistance in tomato.
Graduate and Master Students Committees:
Norma Houston (PhD), 2002-current
Mariana Kirst (PhD) 2002-current
Jeffery Kimbrough (PhD) 2003-current
Song Yoon Lee (MS) 2004-current
Nicolas Ward, 2003-current, Biological Sciences
David Munn, 2004, Biological Sciences
Candace Randell, 2004, Plant Biology Anna Brogan, 2004, Plant BiologyJessica Yester, 2004, BOtany
Mentor for Kenan Fellow:
Benji Downing, (2004-2006), Kenan Fellow, “Gravitational Plant Biology for High Schools”
Regulation of PEP-Carboxylase by Posttranslational Modification HumBOldt Foundation, Lynen-Fellowship,Germany 04/1994 – 05/1996 DM 100,000
“A synthetic peptide that causes
bundling of F-actin in vitro and in situ”.
Technology Transfer, Lawrence Berkeley National Laboratories, Berkeley, USA
(Patent filed 10/19/2003; Inventors: H. Winter, S. Huber, C. Larabell)
PROFESSIONAL SERVICE, AWARDS AND ACTIVITIES
Humboldt-Foundation, 1994-1996, Bonn, Germany
Member of the Council, 2001-2003, University of Osnabrück, Germany
Senate Commission for Women and Equality, 1999-2002, University Osnabrück, Germany
Member of the American Society of Plant Biologists, ASBO, 1997-present
Member of the German Botanical Society, 1998-present, Germany
Member of the International Society of Photosynthesis Research 2001-present
Member of the American Society for Gravitational and Space Biology, 2003-present
Member of the American Association for the Advancement of Science, 1999-present
Member of the Australian “Women in Science” Association (1992-1994)
PUBLICATIONS (peer reviewed, underlined: graduate students and postdocs supervised)
R.E., Brogan, A., Ward, N., Perera, I.Y., Boss, W.F., Brown, C.S., Winter
Sederoff, H. (2005) “Gravity and Light:
Integrating Transcriptional Regulation in Roots.”
Gravitational and Space Bulletin 18(2); June 2005.
Kimbrough, J.M., Brown, C.S., Winter Sederoff, H. (2005) Co-expression and hormonal regulation of genes throughout gravity and mechanical stimulation in the Arabidopsis root apex. Gravitational and Space Bulletin 18(2); June 2005
Kimbrough, J. M., R. Salinas-Mondragon, W. F. BOss, C. S. Brown and H. Winter Sederoff (2004). "The fast and transient transcriptional network of gravity and mechanical stimulation in the Arabidopsis root apex." Plant Physiol 136(1): 2790-805.
Hardin, S. C., H. Winter and S. C. Huber (2004). Phosphorylation of the amino terminus of maize sucrose synthase in relation to membrane association and enzyme activity. Plant Physiol 134(4): 1427-38.
Hardin, S.C., Tang, G.-Q., Scholz, A., Holtgraewe, D., Winter, H., Huber, S.C. (2003) Serine-170 is a calcium-dependent protein kinase targeted phosphorylation site in sucrose synthase that is correlated with protein instability. Plant J. 35:588-603.
Smith, P.M.C., Winter, H., Storer, P.J., Bussell, J.D., Schuller, K.A., Atkins, C.A. (2002) Effect of short-term N2-deficiency on expression of the ureide pathway in cowpea root nodules. Plant Physiol. 129: 1216-1221.
Winter, H., Huber, SC. (2000) Regulation of sucrose metaBOlism in higher plants. Critical Reviews in Biochemistry and Molecular Biology, 35: (4) 253-289.
Winter, H., Huber, SC. (2000) Regulation of sucrose metaBOlism in higher plants. Critical Reviews in Plant Science, 19 (1): 31-67.
Kuzma, M.M., Winter, H., Storer, P., Oresnik, I., Atkins, C.A. and Layzell, D.B. (1999) The site of O2 limitation in soybean nodules. Plant Physiol. 119, 399-408.
Collings, D.A., Winter, H., Wyatt, S.E. and Allen, N.S. (1998) Growth dynamics and cytoskeleton organization during stem maturation and gravity-induced stem bending in Zea mays L. Planta 207, 246-258.
Winter, H., Huber, J.L. and Huber, S.C. (1998) Identification of sucrose synthase as an actin-binding protein. FEBS letters 430, 205-208.
Winter, H., Huber, J.L. and Huber, S.C. (1997) Membrane association of sucrose synthase: Changes during the graviresponse and possible control by phosphorylation. FEBS letters 420, 151-155.
Wadham, C., Winter, H. and Schuller, K.A. (1996) Regulation of soybean nodule phosphoenolpyruvate carboxylase in vivo. Physiol. Plant. 97, 531-535.
Lohaus, G., Winter, H., Riens, B. and Heldt, H.W. (1995) Further Studies of the Phloem Loading Process in Leaves of barley and spinach: The comparison of metabolite concentrations in the apoplastic compartment with those in the cytosolic compartment and in the sieve tubes. BOt. Acta 108, 270-275.
Winter, H., Robinson, D. and Heldt, H.W. (1994) Subcellular volumes and metaBOlite concentrations in spinach leaves. Planta 193, 530-535.
Riens, B., Lohaus, G., Winter, H. and Heldt, H.W. (1994) Production and diurnal utilisation of assimilates in leaves of spinach (Spinacia oleracea) and barley (Hordeum vulgare). Planta, 192, 479-501.
Winter, H., Robinson, D.G., Heldt, H.W. (1993) Subcellular volumes and metabolite concentrations in barley leaves. Planta 191 (2), 180-190.
Winter, H., Lohaus, G. and Heldt, H.W. (1992) Phloem transport of amino acids in relation to their cytosolic levels in barley leaves. Plant Physiol. 99, 996-1004.
BOOK CHAPTERS and other Publications:
Winter, H., Huber, S.C. (2000) Sucrose metabolism and the actin cytoskeleton. In: “Actin: A Dynamic Framework for Multiple Plant Cell Functions.” C.J. Staiger, F. Baluska, D. Volkmann & P. Barlow (eds). Dordrecht, The Netherlands: Kluwer Academic Publisher, pp.119-128.
Huber, S.C., Kaiser, W.M., Toroser, D., Athwal, G.S., Winter, H. and Huber, J.L. (1999) Regulation of sucrose metaBOlism by protein phosphorylation. Stimulation of sucrose synthesis by osmotic stress and 5- aminoimidazole-carboxamide riboside. In: Plant Carbohydrate Biochemistry, J.A. Bryant, M.M. Burrel & N.J. Kruger (eds.), BIOS-Publishers, Blackwood, UK, pp. 61-67.
Huber, S.C., McMicheal, R.W.Jr., Toroser, D., Bachmann, M., Athwal, G.S., Winter, H. and Huber, J.L. (1998). Regulation of cytosolic metabolism by reversible seryl phosphorylation. In: Protein Phosphorylation in Plants. (P. Gadal, M. Kreis, M. Drom, J. Brulfert, C. Bergouniouy and J. Vidal, eds.) University of Paris-Sud, Orsay, France. pp. 101-107.
Lohaus, G., Heineke D., Kruse, A., Leidreiter K., Riens, B., Robinson, D.G., Winter, H., Winzer, T. and Heldt, H.-W. (1998) Compartmentation of metabolites between the subcellular compartments of leaves, the apoplast, the phloem and the storage tissue of different crop plants. In: Regulation of Primary Metabolic Pathways in Plants. N. Krüber, (ed.) Kluwer Academic Publisher.
Heineke, D., Lohaus, G., Winter, H. (1997) Compartmentation of C/N metabolism. In: A Molecular Approach to Primary Metabolism in Plants. C.H. Foyer and P. Quick (eds.),Taylor and Francis, London, UK pp. 205-218.
Leidreiter, K., Kruse, A., Riens, B., Winter, H., Lohaus, G., Robinson, D.G., Heineke, D., and Heldt, H.W. (1995) Subcellular compartmentation of metabolites in plant cells. In: Photosynthesis: From Light to Biosphere. P. Mathis (ed) pp. 483-486 Kluwer Academic Publisher.
Grant Review Panel: NASA Plant Biology 2005
Journals: Journal of Plant Physiology New Phytologist
Planta Plant Journal
Plant Physiology Physiologica Plantarum
Plant Physiology and Biochemistry Advances in Space Biology