Adjunct and Associate Faculty
Area(s) of Expertise
Born in the remote wilds of the Carpathian Mountains in Ukraine, Dr. Slavko Komarnytsky is the Assistant Professor of Pharmacogenomics at the Plants for Human Health Institute, N.C. State University, and Director of the Life Habit Center for Biodiscovery.
Komarnytsky received a B.S. in biology and M.S. in cell biology from Kyiv Shevchenko University in 1998. He earned his Ph.D. in cell and molecular plant biology in 2004 and held research appointments in metabolism and nutrition at Rutgers University prior to joining the food science faculty at N.C. State University in 2011.
His primary scientific interests have been in how dietary bioactive components prevent chronic metabolic diseases and inflammation, with a specific emphasis on the pathological mechanisms of insulin resistance and muscle loss. His scholarly work has set trends in biodiscovery from natural sources and engagement of students and ethnic communities in global health research. He has authored over 40 major scientific publications and gained broad support from government agencies and industry sponsors.
Within this theme, three major initiatives can be used to describe his work:
- Using state of the art applications of pharmacogenomics, nutrigenomic, and bioenergetics technologies to enhance understanding the pathogenesis of metabolic disorders by identifying pathways important in progression of diabetes, obesity and inflammation;
- Collaborating with scientists from various disciplines to access efficacy of botanicals and natural products to restore metabolic balance within liver, muscle and adipose tissues; and
- Supporting education and development of students and scholars, including those located in the developing countries, through biodiscovery from microbial resources, microbial diversity and impact it may have on the safety and health of water users.
Watch a video introduction of Dr. Komarnytsky and his research.
- Berries containing anthocyanins with enhanced methylation profiles are more effective at ameliorating high fat diet-induced metabolic damage, Food and Chemical Toxicology (2018)
- Botanical provenance of traditional medicines from Carpathian Mountains at the Ukrainian-Polish border, Frontiers in Pharmacology (2018)
- Anthocyanins in metabolic health and disease, Nutrigenomics and proteomics in health and disease: towards a systems-level understanding of gene-diet interactions, 2nd edition (2017)
- Antibacterial activity of medicinal plants from The Physicians of Myddvai, a 14th century Welsh medical manuscript, Journal of Ethnopharmacology (2017)
- Health modifying regions in the oat (Avena sativa) genome responsible for beneficial effects on immune and gastrointestinal health, FASEB Journal (2017)
- Metabolic effects of berries with structurally diverse anthocyanins, International Journal of Molecular Sciences (2017)
- Phytoecdysteroid-enriched quinoa seed leachate enhances healthspan and mitochondrial metabolism in Caenorhabditis elegans, Journal of Functional Foods (2017)
- Polyphenols isolated from Acacia mearnsii bark with anti-inflammatory and carbolytic enzyme inhibitory activities, Chinese Journal of Natural Medicines (2017)
- Structural constraints and importance of caffeic acid moiety for anti-hyperglycemic effects of caffeoylquinic acids from chicory, Molecular Nutrition & Food Research (2017)
- Thiazolopyridines improve adipocyte function by inhibiting 11 Beta-HSD1 oxoreductase activity, Journal of Chemistry (2017)