Alfredo is a postdoctoral fellow in the CGIBD basic science T32 doing his research in the PMB department under Dr. Manuel Kleiner. Alfredo operates at the interphase between genome science, analytical chemistry, and microbiology to understand gut microbiota function. He is currently seeking to understand how sources of dietary protein affects the gut microbiota. Alfredo graduated with a bachelor’s degree in Biology from the University of Notre Dame in 2011. He spent three years working on early drug discovery for Tuberculosis at the Infectious Diseases Research Institute in Seattle, WA, before pursuing a Ph.D. in the Genome Science and Technology program jointly sponsored by the University of Tennessee and Oak Ridge National Laboratory. Alfredo attained his Ph.D. in 2020 under the direction of Dr. Robert L. Hettich. Alfredo serves on the Science Advisory Council for the University of Notre Dame as a Young Alumni.
B.S. Biology University of Notre Dame 2011
Ph.D. Genome Science and Technology University of Tennessee 2022
- Considerations for constructing a protein sequence database for metaproteomics , COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2022)
- Morphine and high-fat diet differentially alter the gut microbiota composition and metabolic function in lean versus obese mice , ISME Communications (2022)
- Extracting detailed metabolic information and connections from mammalian gut microbiomes via metaproteomics , University of Tennessee (2020)
- Combining integrated systems-biology approaches with intervention-based experimental design provides a higher-resolution path forward for microbiome research , Behavioral and Brain Sciences (2019)
- Metaproteomics reveals persistent and phylum-redundant metabolic functional stability in adult human gut microbiomes of Crohn’s remission patients despite temporal variations in microbial taxa, genomes, and proteomes , Microbiome (2019)