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The Long and the Short of It

January 30, 2018 | 4:00 pm - 5:00 pm

“The long and the short of it: Characterizing sulfur-cycling in microbial communities with long read sequencing platforms”

Dr. Lizzy Wilbanks
Department of Ecology, Evolution, & Marine Biology
University of California, Santa Barbara

Host

Dr. Manuel Kleiner

Abstract

Metagenomic sequencing of both host-associated microbiomes and free-living microbes has revolutionized our understanding of microbial communities. However, the assembly of genomes and classification of genome fragments (“binning”) from short-read Illumina sequencing remains a major computational challenge. We have been experimenting with three different long read sequencing platforms, PacBio, Illumina synthetic long reads and Oxford Nanopore, to evaluate innovative solutions to the current challenges in metagenomics. Our study system, the “pink berry” consortia are macroscopic, photosynthetic microbial aggregates dominated by two closely associated species: sulfide-oxidizing purple sulfur bacteria (PB-PSB1) and sulfate-reducing bacteria (PB-SRB1), which in previous work, we have demonstrated catalyze a complete sulfur cycle within these aggregates.

This event is hosted by Dr. Manuel Kleiner and will be held in the Stephens Room, 3508 Thomas Hall at 4:00 pm. Refreshments will be served at 3:45 pm.

Details

Date:
January 30, 2018
Time:
4:00 pm - 5:00 pm

Organizer

Dr. Manuel Kleiner