{"id":5199,"date":"2018-05-18T12:03:59","date_gmt":"2018-05-18T16:03:59","guid":{"rendered":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry-new\/?post_type=person&#038;p=5199"},"modified":"2026-07-02T13:39:23","modified_gmt":"2026-07-02T17:39:23","slug":"xiaojing-liu","status":"publish","type":"person","link":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/people\/xiaojing-liu\/","title":{"rendered":"Xiaojing Liu"},"content":{"rendered":"<h2><strong>Research Interests<\/strong><\/h2>\n<p>I am a bioanalytical chemist investigating the fundamental principles of metabolic regulation within intestinal tissues. Operating on the philosophy that metabolic rewiring is a primary driver of disease dynamics\u2014not just a passenger\u2014my research program spans cellular biochemistry to whole-organism physiology to decode complex pathologies. Core research areas include:<\/p>\n<ul>\n<li>Advanced Multi-Omics Workflows: Pioneering integrative liquid chromatography\u2013high-resolution mass spectrometry (LC-HRMS) pipelines across metabolomics, lipidomics, proteomics, and phosphoproteomics in both cell-based and whole-organism models.<\/li>\n<li>Intestinal Metabolic Regulation: Investigating how localized metabolic shifts and tissue-specific mitochondrial function govern systemic health and disease.<\/li>\n<li>Mechanistic Analysis of Drug Action: Bridging cellular biochemistry with organ-specific responses, with a particular focus on how mitochondrial fuel plasticity dictates drug sensitivity (e.g., metformin).<\/li>\n<li>Stable Isotope Flux Analysis: Developing sophisticated in vitro and in vivo tracing methodologies (using 13C-glucose, 13C-glutamine, and 18O tracing) to quantitatively map pathway contributions to specific biological targets.<\/li>\n<\/ul>\n","protected":false},"author":2993,"featured_media":5799,"template":"","meta":{"_acf_changed":false,"source":"","ncst_custom_author":"","ncst_show_custom_author":false,"ncst_dynamicHeaderBlockName":"","ncst_dynamicHeaderData":"","ncst_content_audit_freq":"","ncst_content_audit_date":"","_links_to":"","_links_to_target":""},"group":[219,250,248],"person_tag":[],"class_list":["post-5199","person","type-person","status-publish","has-post-thumbnail","hentry","group-faculty","group-metabolism-and-disease","group-molecular-and-systems-biology"],"acf":[],"_links":{"self":[{"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/person\/5199","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/person"}],"about":[{"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/types\/person"}],"author":[{"embeddable":true,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/users\/2993"}],"version-history":[{"count":10,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/person\/5199\/revisions"}],"predecessor-version":[{"id":19218,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/person\/5199\/revisions\/19218"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/media\/5799"}],"wp:attachment":[{"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/media?parent=5199"}],"wp:term":[{"taxonomy":"group","embeddable":true,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/group?post=5199"},{"taxonomy":"person_tag","embeddable":true,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/person_tag?post=5199"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}