{"id":1733,"date":"2017-08-25T22:12:35","date_gmt":"2017-08-26T02:12:35","guid":{"rendered":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry-new\/people\/fmeille\/"},"modified":"2026-07-02T13:10:36","modified_gmt":"2026-07-02T17:10:36","slug":"fmeille","status":"publish","type":"person","link":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/people\/fmeille\/","title":{"rendered":"Flora Meilleur"},"content":{"rendered":"<h2><strong>Research Interests<\/strong><\/h2>\n<p><span style=\"font-weight: 400\">Research in the Meilleur lab focuses on mapping intra- and intermolecular interactions that govern enzyme function within the microenvironment of the catalytic site. Knowledge of local electrostatics, hydrogen-bonding networks and protonation states of titratable catalytic residues is essential for proper thermodynamic modeling and for predicting binding interactions in molecular recognition and catalysis.We use primarily a combination of X-ray and neutron diffraction and scattering to probe enzyme structure, dynamics and function.<\/span><\/p>\n","protected":false},"author":664,"featured_media":18753,"template":"","meta":{"_acf_changed":false,"source":"","ncst_custom_author":"","ncst_show_custom_author":false,"ncst_dynamicHeaderBlockName":"","ncst_dynamicHeaderData":"","ncst_content_audit_freq":"","ncst_content_audit_date":"","_links_to":"","_links_to_target":""},"group":[219,249],"person_tag":[],"class_list":["post-1733","person","type-person","status-publish","has-post-thumbnail","hentry","group-faculty","group-structural-and-analytical-biochemistry"],"acf":[],"_links":{"self":[{"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/person\/1733","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/person"}],"about":[{"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/types\/person"}],"author":[{"embeddable":true,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/users\/664"}],"version-history":[{"count":10,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/person\/1733\/revisions"}],"predecessor-version":[{"id":19207,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/person\/1733\/revisions\/19207"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/media\/18753"}],"wp:attachment":[{"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/media?parent=1733"}],"wp:term":[{"taxonomy":"group","embeddable":true,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/group?post=1733"},{"taxonomy":"person_tag","embeddable":true,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/person_tag?post=1733"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}