{"id":1883,"date":"2017-10-12T11:06:49","date_gmt":"2017-10-12T15:06:49","guid":{"rendered":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry-new\/?page_id=1883"},"modified":"2023-09-04T13:18:32","modified_gmt":"2023-09-04T17:18:32","slug":"research","status":"publish","type":"page","link":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\n\n\n\n\n<h2 class=\"wp-block-heading\">Solving Big Problems Through Team Science<\/h2>\n\n\n\n<p>Our experts&nbsp;collaborate with scientists on- and off-campus in a number of disciplines related to our research training strengths: molecular and systems biology, structural and analytical biochemistry, and metabolism and disease.<\/p>\n\n\n\n<p>Our cutting-edge research&nbsp;environment is like no other.<\/p>\n\n\n\n<p>We host a comprehensive program in macromolecular structure determination that encompasses nuclear magnetic resonance spectroscopy, X-ray crystallography, neutron diffraction, cryo-electron microscopy, mass spectrometry, and multiple contemporary analytical technology platforms that support the functional characterization of biological structures and systems.<\/p>\n\n\n<div class=\"ncst-labeled-section wp-block-ncst-featured-content ncst-featured-content is-card-style layout-three-column\">\n  <div class=\"ncst-labeled-section__background\">\n    <div class=\"ncst-labeled-section__container\">\n             <div class=\"ncst-labeled-section__content\">\n        \n<div class=\"wp-block-ncst-featured-content\"><a\n    class=\"ncst-content-card wp-block-ncst-content-card with-image with-cta\"\n    href=\"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/group\/molecular-and-systems-biology\/\"\n    data-ua-cat=\"Content Card\"\n    data-ua-action=\"Content Card Click\"\n    data-ua-label=https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/group\/molecular-and-systems-biology\/\n  >\n  \n\n          <div class=\"content-card__image-container\">\n        <div class=\"content-card__image-background\">\n          <img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"844\" \n            class=\"content-card__image wp-image-5194\" \n            alt=\"Colleen Doherty and student in Phytotron.\" \n            src=\"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Molecular_Systems.jpg\" \n            style=\"aspect-ratio: 16\/9; object-fit: cover; \"\n srcset=\"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Molecular_Systems.jpg 1500w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Molecular_Systems-300x169.jpg 300w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Molecular_Systems-768x432.jpg 768w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Molecular_Systems-1024x576.jpg 1024w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Molecular_Systems-1200x675.jpg 1200w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Molecular_Systems-950x535.jpg 950w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Molecular_Systems-600x338.jpg 600w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Molecular_Systems-460x259.jpg 460w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Molecular_Systems-230x129.jpg 230w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/>\n        <\/div>\n      <\/div>\n    \n    <div class=\"content-card__text-container\">\n      \n                          <h3 class=\"content-card__headline\">Molecular and Systems Biology <\/h3>\n              \n\n      \t      \t        <p class=\"content-card__teaser\">Research and training in molecular and systems biology focuses on understanding gene expression and molecular details of plant, animal, and microbial systems.<\/p>\n\t      \t    \n              <p class=\"content-card__cta\">Explore the <span class=nowrap>labs&nbsp;<span class=\"arrow-indicator\"><svg class=\"wolficon wolficon-arrow-right-bold\" role=\"img\"  aria-hidden=\"true\">\n            \n            <use xlink:href=\"#wolficon-arrow-right-bold\">\n        <\/svg><\/span><\/span><\/p>\n          <\/div>\n\n  <\/a>\n\n\n<a\n    class=\"ncst-content-card wp-block-ncst-content-card with-image with-cta\"\n    href=\"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/group\/structural-and-analytical-biochemistry\/structural-and-analytical-biochemistry\"\n    data-ua-cat=\"Content Card\"\n    data-ua-action=\"Content Card Click\"\n    data-ua-label=https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/group\/structural-and-analytical-biochemistry\/structural-and-analytical-biochemistry\n  >\n  \n\n          <div class=\"content-card__image-container\">\n        <div class=\"content-card__image-background\">\n          <img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"844\" \n            class=\"content-card__image wp-image-5196\" \n            alt=\"Researchers in the lab discussing their findings.\" \n            src=\"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Structural_Analytical_-Biochemistry.jpg\" \n            style=\"aspect-ratio: 16\/9; object-fit: cover; \"\n srcset=\"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Structural_Analytical_-Biochemistry.jpg 1500w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Structural_Analytical_-Biochemistry-300x169.jpg 300w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Structural_Analytical_-Biochemistry-768x432.jpg 768w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Structural_Analytical_-Biochemistry-1024x576.jpg 1024w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Structural_Analytical_-Biochemistry-1200x675.jpg 1200w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Structural_Analytical_-Biochemistry-950x535.jpg 950w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Structural_Analytical_-Biochemistry-600x338.jpg 600w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Structural_Analytical_-Biochemistry-460x259.jpg 460w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Research-Structural_Analytical_-Biochemistry-230x129.jpg 230w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/>\n        <\/div>\n      <\/div>\n    \n    <div class=\"content-card__text-container\">\n      \n                          <h3 class=\"content-card__headline\">Structural and Analytical Biochemistry<\/h3>\n              \n\n      \t      \t        <p class=\"content-card__teaser\">Research and training centers on detailed structural and functional analysis of macromolecules using sophisticated modern technologies.<\/p>\n\t      \t    \n              <p class=\"content-card__cta\">Find out <span class=nowrap>more&nbsp;<span class=\"arrow-indicator\"><svg class=\"wolficon wolficon-arrow-right-bold\" role=\"img\"  aria-hidden=\"true\">\n            \n            <use xlink:href=\"#wolficon-arrow-right-bold\">\n        <\/svg><\/span><\/span><\/p>\n          <\/div>\n\n  <\/a>\n\n\n<a\n    class=\"ncst-content-card wp-block-ncst-content-card with-image with-cta\"\n    href=\"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/group\/metabolism-and-disease\/\"\n    data-ua-cat=\"Content Card\"\n    data-ua-action=\"Content Card Click\"\n    data-ua-label=https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/group\/metabolism-and-disease\/\n  >\n  \n\n          <div class=\"content-card__image-container\">\n        <div class=\"content-card__image-background\">\n          <img loading=\"lazy\" decoding=\"async\" width=\"1500\" height=\"844\" \n            class=\"content-card__image wp-image-5340\" \n            alt=\"\" \n            src=\"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Aaila.jpg\" \n            style=\"aspect-ratio: 16\/9; object-fit: cover; \"\n srcset=\"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Aaila.jpg 1500w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Aaila-300x169.jpg 300w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Aaila-768x432.jpg 768w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Aaila-1024x576.jpg 1024w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Aaila-1200x675.jpg 1200w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Aaila-950x535.jpg 950w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Aaila-600x338.jpg 600w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Aaila-460x259.jpg 460w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Aaila-230x129.jpg 230w\" sizes=\"auto, (max-width: 1500px) 100vw, 1500px\" \/>\n        <\/div>\n      <\/div>\n    \n    <div class=\"content-card__text-container\">\n      \n                          <h3 class=\"content-card__headline\">Metabolism and Disease<\/h3>\n              \n\n      \t      \t        <p class=\"content-card__teaser\">Research and training opportunities examine central metabolic pathways important for normal processes in plants and animals, and their alterations in various disease states.<\/p>\n\t      \t    \n              <p class=\"content-card__cta\">View research <span class=nowrap>labs&nbsp;<span class=\"arrow-indicator\"><svg class=\"wolficon wolficon-arrow-right-bold\" role=\"img\"  aria-hidden=\"true\">\n            \n            <use xlink:href=\"#wolficon-arrow-right-bold\">\n        <\/svg><\/span><\/span><\/p>\n          <\/div>\n\n  <\/a>\n<\/div>\n\n      <\/div>\n    <\/div>\n  <\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Strengthening Research with <br>Shared Resources<\/h2>\n\n\n\n<p>The <a href=\"https:\/\/research.ncsu.edu\/\" target=\"_blank\" rel=\"noreferrer noopener\">Office of Research and Innovation<\/a> (ORI) manages six university core shared research facilities that house a variety of state-of-the-art instruments. Each of these facilities are staffed by scientists that offer hands-on training, specialized research services and project consultation.<\/p>\n\n\n\n<div class=\"wp-block-ncst-button is-style-secondary\"><a href=\"https:\/\/research.ncsu.edu\/shared-core-facilities\/\" class=\"btn ncst-block__button-link\" data-ncst-lightbox=\"false\" data-ua-cat=\"Button Block\" data-ua-action=\"Button Click\" data-ua-label=\"https:\/\/research.ncsu.edu\/shared-core-facilities\/\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"text\">Explore Core Facilities<\/span><span class=\"arrow-indicator\">\n<svg class=\"wp-block-ncst-wolficon wolficon\" role=\"img\" aria-hidden=\"true\"><use xlink:href=\"#wolficon-arrow-right-bold\" \/><\/svg>\n<\/span><\/a><\/div>\n\n\n\n<h3 class=\"wp-block-heading\">Molecular Education, Technology and Research Innovation Center<\/h3>\n\n\n\n<figure class=\"wp-block-image alignwide size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/instruments-1500-1024x576.jpg\" alt=\"METRIC\" class=\"wp-image-5115\" srcset=\"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/instruments-1500-1024x576.jpg 1024w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/instruments-1500-300x169.jpg 300w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/instruments-1500-768x432.jpg 768w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/instruments-1500.jpg 1500w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/instruments-1500-1200x675.jpg 1200w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/instruments-1500-950x535.jpg 950w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/instruments-1500-600x338.jpg 600w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/instruments-1500-460x259.jpg 460w, https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/instruments-1500-230x129.jpg 230w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p>The Molecular Education, Technology and Research Innovation Center (METRIC)  is focused on chemical and biochemical structural characterization utilizing mass spectrometry, magnetic resonance spectroscopy and x-ray crystallography. <\/p>\n\n\n\n<p>A partnership among <a rel=\"noreferrer noopener\" href=\"http:\/\/cals.ncsu.edu\" target=\"_blank\">CALS<\/a>, <a href=\"http:\/\/sciences.ncsu.edu\">College of Sciences<\/a>, and ORIED, the goal of METRIC is to become the leading chemical and biochemical characterization facility in the Southeast.<\/p>\n\n\n\n<div class=\"wp-block-ncst-button is-style-secondary\"><a href=\"https:\/\/research.ncsu.edu\/metric\/about\/\" class=\"btn ncst-block__button-link\" data-ncst-lightbox=\"false\" data-ua-cat=\"Button Block\" data-ua-action=\"Button Click\" data-ua-label=\"https:\/\/research.ncsu.edu\/metric\/about\/\" target=\"_blank\" rel=\"noreferrer noopener\"><span class=\"text\">Explore METRIC<\/span><span class=\"arrow-indicator\">\n<svg class=\"wp-block-ncst-wolficon wolficon\" role=\"img\" aria-hidden=\"true\"><use xlink:href=\"#wolficon-arrow-right-bold\" \/><\/svg>\n<\/span><\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Solving Big Problems Through Team Science Our experts&nbsp;collaborate with scientists on- and off-campus in a number of disciplines related to our research training strengths: molecular and systems biology, structural and&hellip;<\/p>\n","protected":false},"author":43,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"source":"","ncst_custom_author":"","ncst_show_custom_author":false,"ncst_dynamicHeaderBlockName":"ncst\/split-header","ncst_dynamicHeaderData":"{\"backgroundColor\":\"gray_800\",\"pageIntro\":\"Our work impacts everything from human health to the global food supply. \",\"imageID\":5339,\"imageURL\":\"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-content\/uploads\/sites\/35\/2018\/05\/Xu_lab.jpg\"}","ncst_content_audit_freq":"","ncst_content_audit_date":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-1883","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/pages\/1883","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/users\/43"}],"replies":[{"embeddable":true,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/comments?post=1883"}],"version-history":[{"count":9,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/pages\/1883\/revisions"}],"predecessor-version":[{"id":13038,"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/pages\/1883\/revisions\/13038"}],"wp:attachment":[{"href":"https:\/\/cals.ncsu.edu\/molecular-and-structural-biochemistry\/wp-json\/wp\/v2\/media?parent=1883"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}