Type: Associate Faculty
PhD, Vanderbilt University
Office: 132 David Clark Labs
Research in the Planchart lab combines high throughput techniques, including next-gen sequencing, proteomics, and transcriptomics, to understand how environmental factors affect vertebrate embryonic development. Currently, we are focused on identifying genetic modifiers of craniofacial development that can be modulated by changes in the environment during embryogenesis. Specifically, we are interested in discovering regulatory genes that confer developmental plasticity, thus buffering an organism from drastic changes in its developmental program that result from changes in its environment.
Cheng KC, Hinton DE, Mattingly CJ, Planchart A. (2012). Aquatic models, genomics and chemical risk management. Comp Biochem Physiol C Toxicol Pharmacol. 155(1): 169–73.
Planchart A, Mattingly CJ. (2010). 2,3,7,8-Tetrachlorodibenzo-p-dioxin upregulates FoxQ1b in zebrafish jaw primordium. Chem Res Toxicol. 23(3): 480–7.
Mattingly CJ, Hampton TH, Brothers KM, Griffin NE, Planchart A. (2009). Perturbation of defense pathways by low-dose arsenic exposure in zebrafish embryos. Environ Health Perspect. 117(6): 981–7.
Coffman JA, Coluccio A, Planchart A, Robertson AJ. (2009). Oral-aboral axis specification in the sea urchin embryo III. Role of mitochondrial redox signaling via H2O2. Dev Biol. 330(1): 123–30.